Evaluation of radioactivity in the bladder after injection of 131 I hippurate into lateral ventricles of hydrocephalic patients.

Introduction This paper is a report on a computer simulation based on Bladder-scans which were recorded from hydrocephalic patients between 1965 and 1970 at the University Hospital, Rotterdam. From these scans, which show the accumulation of radioactive 1311 hippurate molecules in the bladder, values were derived for the rates at which the molecules left the cerebral ventricles and reached the bladder. The state of both systems could then be assessed, as could the state of renal function. A correlation study was also set up in which the data were compared with clinical data in an attempt to find out whether the bladder-scans gave any indication of CSF resorption (physiological or pathological) and, consequently, any indications for the prognosis for patients with hydrocephalus.